What is the impact of Huntington's disease on life expectancy and cognitive function?
Huntington's disease (HD) is a fatal genetic disorder that affects muscle coordination and cognitive function. It is caused by a mutation in the huntingtin gene, which results in the production of a toxic protein that damages brain cells.
HD typically affects people in their 30s or 40s, although it can develop at any age. The disease progresses over time, and symptoms gradually worsen. In the early stages, people with HD may experience clumsiness, difficulty with balance, and speech problems. As the disease progresses, they may develop involuntary movements, such as chorea, which is characterized by uncontrollable jerking and twitching of the limbs and face.
HD also has a significant impact on cognitive function. People with HD may experience problems with memory, attention, and judgment. They may also develop dementia, which can lead to a loss of independence and the ability to care for themselves.
The life expectancy for people with HD is typically 15-20 years after the onset of symptoms. However, some people may live for longer or shorter periods of time, depending on the severity of their disease.
Related Questions:
- What is the most common symptom of Huntington's disease?
- What is the genetic basis of Huntington's disease?
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- What is the treatment for Huntington's disease?
- What is the prognosis for someone with Huntington's disease?
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