Why is it Difficult to Prevent Recurrence in Patients with Triple Negative Breast Cancer
Triple negative breast cancer (TNBC) is a particularly aggressive type of breast cancer that is characterized by the lack of expression of estrogen, progesterone, and HER2 receptors. This makes it difficult to treat with targeted therapies that are effective against other types of breast cancer.
In addition, TNBC is more likely to recur than other types of breast cancer. The 5-year recurrence rate for TNBC is about 30%, compared to about 15% for other types of breast cancer. This is thought to be due to the fact that TNBC cells are more likely to be able to evade the immune system and spread to other parts of the body.
There are a number of factors that can contribute to the difficulty of preventing recurrence in patients with TNBC, including:
- The lack of effective targeted therapies
- The increased likelihood of TNBC cells evading the immune system
- The tendency of TNBC to spread to other parts of the body
- The lack of screening tools that can detect TNBC early
- The lack of lifestyle modifications that can prevent TNBC
Despite the challenges, there are a number of things that can be done to reduce the risk of recurrence in patients with TNBC, including:
- Receiving adjuvant therapy, such as chemotherapy, radiation therapy, or hormone therapy
- Participating in clinical trials
- Making lifestyle changes, such as eating a healthy diet and exercising regularly
- Getting regular mammograms and breast exams
相关问题
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